CPC Class B33Y

The present disclosure describes apparatuses and techniques for room temperature three-dimensional (3D) printing using edible printing materials. In some aspects, a 3D printer includes a printing platform configured to receive the extruded edible printing material from the printing cartridge, a cartridge receiver configured to hold an integrated printing cartridge that contains an edible printing material that can be extruded at room temperature, and a printing target. The position of the printing platform can be adjusted vertically and the position of the cartridge receiver can be adjusted in a plane perpendicular to the printing platform. The printing target is configured to allow extrusion of the edible printing material at precise and repeatable locations.

The invention relates to devices and methods for designing and manufacturing customized footwear, and components thereof. An exemplary method includes a method of designing at least a portion of a sole of an article of footwear customized for a user. The method includes the steps of determining at least one input parameter related to a user, analyzing the at least one input parameter to determine at least one performance metric of a foot of the user, and determining at least one customized structural characteristic of at least a portion of a sole of an article of footwear for the user based on the performance metric.

A cushioning member includes a first lattice structure and a second lattice structure. The first lattice structure includes a first network of struts and nodes with voids defined between the struts and nodes. The second lattice structure includes a second network of struts and nodes with voids defined between the struts and nodes. The first network of struts and nodes is interwoven with the second network of struts and nodes such that the first network of struts and nodes extends through the voids in the second network of struts and nodes.

The present application relates to adaptive surface surgical guiding apparatuses. A surgical guiding apparatus may include one or more rigid portions configured to attach to a first region of an underlying anatomical surface. The surgical guiding apparatus may further include a variable deformable portion coupled to the one or more rigid portions, the variable deformable portion configured to conform to a shape of a second region of the underlying anatomical surface to provide a stable attachment of the surgical guiding apparatus to the underlying anatomical surface. The present disclosure further provides methods for manufacturing surgical guiding apparatuses and uses of the apparatuses for placement onto an underlying anatomical surface.

Methods and materials for making complex, living, vascularized tissues for organ and tissue replacement, especially complex and/or thick, structures, such as liver tissue is provided. Tissue lamina is made in a system comprising an apparatus having (a) a first mold or polymer scaffold, a semi-permeable membrane, and a second mold or polymer scaffold, wherein the semi-permeable membrane is disposed between the first and second molds or polymer scaffolds, wherein the first and second molds or polymer scaffolds have means defining microchannels positioned toward the semi-permeable membrane, wherein the first and second molds or polymer scaffolds are fastened together; and (b) animal cells. Methods for producing complex, three-dimensional tissues or organs from tissue lamina are also provided.

The implant fixation systems disclosed herein include an implant manufactured with, or coupled to, one or more implant fixation devices used to secure the implant to bone. Various implant fixation device embodiments have an engagement element with a concave engagement tip, a guiding element defining a planned trajectory along which the engagement element is configured to move, and an adjustment element configured to move the engagement element along the planned trajectory. Moving the engagement element along the planned trajectory causes the concave engagement tip to enter a bone in a first position and rotate within the bone to a second position. Continuing to move the engagement element along the planned trajectory may cause the concave engagement tip to undergo translational movement from the second position to a third position, thereby pulling the implant towards the bone and exerting compression forces on the bone.