CPC Class B33Y

Disclosed herein is an orthopedic implant device comprising a porous structure, approximating the shape of a bone, and having modulus of elasticity similar to that of said bone. In one embodiment, further disclosed herein is a method of treating injuries or diseases affecting bones or muscles comprising providing an orthopedic implant device, wherein the orthopedic implant device comprising a porous structure, approximating the shape of a bone, and having a modulus of elasticity similar to that of bone, and using the orthopedic implant device to treat injuries and diseases affecting bones and muscles in a mammal. In another embodiment, disclosed herein is a method of manufacturing an orthopedic implant device using an additive manufacturing (AM) method.

A printed tissue construct comprises one or more tissue patterns, where each tissue pattern comprises a plurality of viable cells of one or more predetermined cell types. A network of vascular channels interpenetrates the one or more tissue patterns. An extracellular matrix composition at least partially surrounds the one or more tissue patterns and the network of vascular channels. A method of printing a tissue construct with embedded vasculature comprises depositing one or more cell-laden filaments, each comprising a plurality of viable cells, on a substrate to form one or more tissue patterns. Each of the one or more tissue patterns comprises one or more predetermined cell types. One or more sacrificial filaments, each comprising a fugitive ink, are deposited on the substrate to form a vascular pattern interpenetrating the one or more tissue patterns. The vascular pattern and the one or more tissue patterns are at least partially surrounded with an extracellular matrix composition. The fugitive ink is then removed to create vascular channels in the extracellular matrix composition, thereby forming an interpenetrating vascular network in a tissue construct.

A system uses microwave energy to remove support material from a three-dimensional printed object with reduced risk of damage to the object. The system includes a microwave source, a three port device, a susceptor, a temperature sensor, and a controller. The controller operates the microwave source to direct microwave energy into a first port of the three port device, which emits the microwave at a second port of the three port device to irradiate the three-dimensional object and melt the support material. Reflected microwave increases as the amount of support material contacting the object is reduced and enters the second port of the three port device, which directs the reflected energy to the susceptor coupled to a third port of the three port device. The controller monitors the signal generated by the temperature sensor and deactivates the microwave source in response to a predetermined condition being reached.

The present invention relates to a process for the bonding of material for the production of three-dimensional objects by selective heating via a laser of wavelength from 100 to 3000 nm. The beam spot may be a focused or unfocused beam spot, or may indeed be spread, as is the case with the diode laser, where the bars may have a stacked arrangement. The selectivity of the melting process is achieved via the application of an absorber to certain subregions of a layer composed of a pulverulent substrate, and then heating of the absorber by laser radiation of wavelength from 100 to 3000 nm. The heated absorber transfers the energy present therein to its surrounding pulverulent substrate, which is melted thereby and, after cooling, has firm cohesive bonding.

An apparatus (1) for additive manufacturing of three-dimensional objects (3) by successive, selective layer-by-layer exposure and thus successive, selective layer-by-layer solidification of construction material layers of construction material (4) that can be solidified by means of an energy beam. The apparatus can include a process chamber (14) comprising a working plane (A) with a first working plane area (A1) and another working plane area (A2), a coating device (6) provided for forming construction material layers to be exposed selectively and to be solidified selectively in the construction plane (E) and comprising a coating element assembly group (8) which is movably supported, at least one coating element, a shielding device (18) provided for shielding the second working plane area (A2), wherein the shielding device (18) can include at least one shielding band (20) guided movably along supporting points (19).

A method of fabricating a part by additive fabrication, in particular by melting or sintering particles of powder by means of a high energy beam. The method includes supplying a digital model of a part to be fabricated; orienting the model relative to a construction direction for constructing the part; modifying the model by adding a sacrificial balancing fraction configured so as to balance the residual stresses that appear in the part while it is being fabricated; making a rough part layer by layer using an additive fabrication technique on the basis of the model as modified in this way, the layers being stacked in the construction direction; and using a material-removal method to eliminate the sacrificial portion from the rough part as results from the sacrificial balancing fraction of the model, thereby obtaining the part that is to be fabricated.